COVID-19 virusiconHome
HomeSearchDownloadsResourcesAbout
SearchDownloadsResourcesAbout

Identifier
NSP10

Gene
ORF1ab
Protein name
Replicase polyprotein 1ab – Non-structural protein 10
Localization
cytoplasm
Uniprot
P0DTD1
Description

Plays a pivotal role in viral transcription by stimulating both nsp14 3'-5' exoribonuclease and nsp16 2'-O-methyltransferase activities. Therefore plays an essential role in viral mRNAs cap methylation. (From UniProt)

Information & downloads

Downloads

These downloads are specific to this bait. Full data set downloads can be found on the downloads page.

Sequence

AGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQ
Copy
Visualization

Specificity

Plot the specificity of a prey versus its spectral count. The specificty of a prey is calculated as the fold change in the spectral count relative to the average across all other baits. Any other conditions/treatments for the query bait are ignored when calculating the average. Every other bait can contribute a single value when calculting the average, and this value is the maximum spectral count across any conditions present for that bait.

Orange points have infinite specificty. Hover over a point to see its label or click on a point to add a label to the plot.

Select a condition

Options

Zoom:

Compare conditions

Compare the spectral counts between two different conditions. Any prey passing the option criteria for at least one bait will be displayed. Hover over a point to see its label or click on a point to add a label to the plot.

Select a pair of conditions

Options

Zoom:

Preys

Condition legend
  • Ct: C-terminal tag
  • Nt: N-terminal tag
  • SC: spectral counts, calculated as the average spectral count between replicates minus the average detect in controls
  • Spec: specificity, calculated as the fold enrichment of a prey relative to all other bait proteins
  • FDR: false discovery rate
Prey
ID (Entrez / UniProt)ConditionsProfile
C-terminal tag (Ct)N-terminal tag (Nt)
S.C.
Spec.
FDR
S.C.
Spec.
FDR
ARID1A8289 / O1449726.4228.1101.421.510.34
ARID2196528 / Q68CP912.6717.170.014.676.330.28
ARID1B57492 / Q8NFD51022.6101.53.390.07
ATRX546 / P461005.173.930.01---
PHGDH26227 / O43175532.50.1613.587.750
SAP13079595 / Q9H0E34.1721.640.012.6713.860.19
ASRGL180150 / Q7L26625.2025.20
MBOAT779143 / Q96N661.330.130.173.830.390.01
IPO1151194 / Q9UI260.835.410.184.3328.220.01
CLPX10845 / O76031---6.671.360.01
CLASRP11129 / Q8N2M8---2.5Infinity0
PPHLN151535 / Q8NEY8---39.750
IRF2BPL64207 / Q9H1B7---3780
FNIP196459 / Q8TF40---220.80