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Identifier
NSP7

Gene
ORF1ab
Protein name
Replicase polyprotein 1ab – Non-structural protein 7
Localization
cytoplasm
Uniprot
P0DTD1
Description

Plays a role in viral RNA synthesis. Forms a hexadecamer with nsp8 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers. (From UniProt)

Information & downloads

Downloads

These downloads are specific to this bait. Full data set downloads can be found on the downloads page.

Sequence

SKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQ
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Visualization

Specificity

Plot the specificity of a prey versus its spectral count. The specificty of a prey is calculated as the fold change in the spectral count relative to the average across all other baits. Any other conditions/treatments for the query bait are ignored when calculating the average. Every other bait can contribute a single value when calculting the average, and this value is the maximum spectral count across any conditions present for that bait.

Orange points have infinite specificty. Hover over a point to see its label or click on a point to add a label to the plot.

Select a condition

Options

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Compare conditions

Compare the spectral counts between two different conditions. Any prey passing the option criteria for at least one bait will be displayed. Hover over a point to see its label or click on a point to add a label to the plot.

Select a pair of conditions

Options

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Preys

Condition legend
  • Ct: C-terminal tag
  • Nt: N-terminal tag
  • SC: spectral counts, calculated as the average spectral count between replicates minus the average detect in controls
  • Spec: specificity, calculated as the fold enrichment of a prey relative to all other bait proteins
  • FDR: false discovery rate
Prey
ID (Entrez / UniProt)ConditionsProfile
C-terminal tag (Ct)N-terminal tag (Nt)
S.C.
Spec.
FDR
S.C.
Spec.
FDR
CDK138621 / Q1400444.7517.37036.7514.260
TASOR23272 / Q9UK6132.5810.920.0346.5815.610
CCP1109738 / O4330328.2510.6405.251.980.36
NRIP18204 / P4855226.177.74017.675.230.16
AVEN57099 / Q9NQS124.9220.2902.421.970.41
PRKDC5591 / P7852724.56.890.01308.430
TTC379652 / Q6PGP71820.35030.534.480
LAS1L81887 / Q9Y4W216.834.940.1923.336.840
HJURP55355 / Q8NCD316.2510.560.327.7518.040
MCM74176 / P3399313.174.070.017.672.370.19
UGGT156886 / Q9NYU290.360---
SLC9A3R19368 / O147458.9222.60.01---
CCDC138165055 / Q96M897.582.720.0219.587.020
TTC2755622 / Q6P3X37.56.960---
ESPL19700 / Q14674760.6703.530.330
VPS5451542 / Q9P1Q06.516909.52470
APAF1317 / O147276.537.560---
ICE123379 / Q9Y2F5618.350---
CAMSAP1157922 / Q5T5Y35.581.20.5554.0811.590
RUNDC1146923 / Q96C3452.52084.040
PRR14L253143 / Q5THK14.8331.470.011.338.670.17
KIFC13833 / Q9BW194Infinity03Infinity0.04
ZGRF155345 / Q86YA344.7303.54.140
GNAS2778 / O954673.833.020.018.336.570
PPM1B5495 / O756883.832.250.01---
PTPN15770 / P180313.750.380.0210.251.030
WDR72256764 / Q3MJ133.50.38030.320
JAK13716 / P234583.171.80.1612.176.920
P4HB5034 / P0723730.310---
CLSPN63967 / Q9HAW438.210---
ANAPC751434 / Q9UJX32.5Infinity0.0513.5Infinity0
HSP90B17184 / P146252.50.220---
VAC1455697 / Q08AM623.470.0535.20
HUWE110075 / Q7Z6Z72Infinity0.058Infinity0
SREBF16720 / P3695620.160.055.50.440
CDK91025 / P507502Infinity0.055.5Infinity0
ZNF46010794 / Q14592234.670.056.5112.670
CAD790 / P277081.830.180.163.830.380.01
ANAPC551433 / Q9UJX41.58.670.073.520.220
SNX1457231 / Q9Y5W71.50.250.0730.510
NCAPD29918 / Q150211.424.710.236.9222.950.01
TTC7A57217 / Q9ULT013.060.1824.470
CEP13122994 / Q9UPN4---4.53.770
CPS11373 / P31327---42.140
CPNE18904 / Q99829---4.171.860.01
TXNL19352 / O43396---15.52.510
CLPX10845 / O76031---5.171.040.01
TTI19675 / O43156---6.0847.610.01
ZFP1162239 / Q6P2D0---4.5Infinity0
UBR3130507 / Q6ZT12---314.180
RTTN25914 / Q86VV8---3.8327.210.01
NF14763 / P21359---4.1711.60.01
DNM21785 / P50570---3260
ASMTL8623 / O95671---4.835.10.01
NPEPPS9520 / P55786---2.51.970
AP2A1160 / O95782---3.5910
WDR3557539 / Q9P2L0---4.677.210.01
STRIP257464 / Q9ULQ0---2.5650
TUT423318 / Q5TAX3---3130
NSMCE356160 / Q96MG7---2Infinity0